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VulnerabilityPublished

CVE-2025-12921: OpenClinica Community Edition · Injection

Source GCVE Database

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Authoritative record:CVE-2025-12921· Medium 5.3

Public exploit available · CVSS 5.3 Medium.

Data as of 4 Nov 2026, 17:16 UTC

CVSS 4.0 base score
5.3Medium
How severe the flaw is on the 0–10 CVSS scale.
Affects
OpenClinica Community Edition up to 3.12.2
CVSS:4.0/AV:N/AC:L/AT:N/PR:L/UI:N/VC:L/VI:N/VA:N/SC:N/SI:N/SA:N/E:P

Exploitation evidence

  1. Disclosed: evidence found.

    CVE published 9 Nov 2025

  2. Detectable: no evidence on record.

    No public nuclei template indexed

  3. Weaponized: evidence found.

    CVSS exploit maturity: proof of concept public

  4. Exploited in the wild: no evidence on record.

    Not in CISA KEV and no source reports exploitation

  5. Observed by OffSeq Mirage: no evidence on record.

    No attack traffic recorded by OffSeq Mirage sensors

A missing step is not evidence of safety. Sources: cve.org (opens in a new tab), CVSS vector, the Metasploit, Exploit-DB and nuclei-templates index as of 4 Nov 2026.

Description

A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file /ImportCRFData?action=confirm of the component CRF Data Import. Such manipulation of the argument xml_file leads to xml injection. It is possible to launch the attack remotely. The exploit has been disclosed to the public and may be used. The vendor was contacted early about this disclosure but did not respond in any way.

References

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