CVE-2025-12922: OpenClinica Community Edition · Path Traversal
Source GCVE Database
Public exploit available · CVSS 5.3 Medium.
Data as of 4 Nov 2026, 17:16 UTC
- Affects
- OpenClinica Community Edition up to 3.12.2
CVSS:4.0/AV:N/AC:L/AT:N/PR:L/UI:N/VC:L/VI:L/VA:L/SC:N/SI:N/SA:N/E:PExploitation evidence
Disclosed: evidence found.
CVE published 10 Nov 2025
Detectable: no evidence on record.
No public nuclei template indexed
Weaponized: evidence found.
CVSS exploit maturity: proof of concept public
Exploited in the wildExploited: no evidence on record.
Not in CISA KEV and no source reports exploitation
Observed by OffSeq MirageSeen by Mirage: no evidence on record.
No attack traffic recorded by OffSeq Mirage sensors
A missing step is not evidence of safety. Sources: cve.org (opens in a new tab), CVSS vector, the Metasploit, Exploit-DB and nuclei-templates index as of 4 Nov 2026.
Description
A vulnerability was found in OpenClinica Community Edition up to 3.12.2/3.13. This affects an unknown part of the file /ImportCRFData?action=confirm of the component CRF Data Import. Performing manipulation of the argument xml_file results in path traversal. The attack can be initiated remotely. The exploit has been made public and could be used. The vendor was contacted early about this disclosure but did not respond in any way.
References
- nvd.nist.gov/vuln/detail/CVE-2025-12922 (opens in a new tab)
- github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-rce.md (opens in a new tab)
- github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-rce.md (opens in a new tab)
- vuldb.com (opens in a new tab)
- vuldb.com (opens in a new tab)
- vuldb.com (opens in a new tab)