CVE-2025-54305: Thermo Fisher Torrent Suite Django application · Authentication Bypass by Spoofing
Source CVE Database V5
Not known to be exploited · CVSS 7.8 High.
Data as of 26 Oct 2026, 14:05 UTC
- EPSS
- 0.1% chance of exploitation in 30 days – higher than 4% of CVEsExploit Prediction Scoring System: the likelihood attackers will use this flaw soon.
CVSS:3.1/AV:L/AC:L/PR:L/UI:N/S:U/C:H/I:H/A:HExploitation evidence
Disclosed: evidence found.
CVE published 4 Dec 2025
Detectable: no evidence on record.
No public nuclei template indexed
Weaponised: no evidence on record.
No public exploit code indexed in Metasploit or Exploit-DB
Exploited in the wildExploited: no evidence on record.
Not in CISA KEV and no source reports exploitation
Observed by OffSeq MirageSeen by Mirage: no evidence on record.
No attack traffic recorded by OffSeq Mirage sensors
A missing step is not evidence of safety. Sources: cve.org (opens in a new tab), the Metasploit, Exploit-DB and nuclei-templates index as of 26 Oct 2026.
What to do
AI-suggested
European organizations should implement strict access controls to limit local server access only to trusted personnel. Network segmentation and host-based firewalls can reduce exposure of vulnerable servers. Immediate review and removal or modification of the LocalhostAuthMiddleware in the application code is essential to prevent automatic localhost authentication. If source code modification is not feasible, deploy compensating controls such as mandatory multi-factor authentication for all administrative access and enhanced logging and monitoring of local user activities. Regular audits should verify that no unauthorized local accounts exist. Organizations should also engage with Thermo Fisher for patches or updates addressing this vulnerability. In the interim, consider isolating vulnerable systems within secure environments and employing intrusion detection systems to alert on suspicious local access patterns. Training and awareness for system administrators about the risks of local access abuse are also recommended.
Description
An issue was discovered in the Thermo Fisher Torrent Suite Django application 5.18.1. One of the middlewares included in this application, LocalhostAuthMiddleware, authenticates users as ionadmin if the REMOTE_ADDR property in request.META is set to 127.0.0.1, to 127.0.1.1, or to ::1. Any user with local access to the server may bypass authentication.
References
- thermofisher.com/us/en/home/life-science/sequencing/next-generation-sequencing/ion-torrent-next-generation-sequencing-workflow/ion-torrent-next-generation-sequencing-data-analysis-workflow/ion-torrent-suite-software.html (opens in a new tab)
- assets.thermofisher.com/TFS-Assets/LSG/manuals/MAN0026163-Torrent-Suite-5.18-UG.pdf (opens in a new tab)
- documents.thermofisher.com/TFS-Assets/CORP/Product-Guides/Ion_OneTouch_2_and_Torrent_Suite_Software.pdf (opens in a new tab)