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VulnerabilityPublished Updated

CVE-2026-45645: Microsoft 365 Apps for Enterprise · Untrusted Pointer Dereference

Affects Microsoft 365 Apps for EnterpriseSource CVE Database V5

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Not known to be exploited · CVSS 7.8 High · fixed in 16.0.5556.1001 : patch Microsoft 365 Apps for Enterprise soon.

Data as of 30 Oct 2026, 06:59 UTC

CVSS 3.1 base score
7.8High
How severe the flaw is on the 0–10 CVSS scale.
EPSS
0.3% chance of exploitation in 30 days – higher than 31% of CVEsExploit Prediction Scoring System: the likelihood attackers will use this flaw soon.
Patch
Available – fixed in 16.0.5556.1001, 16.110.26061317
CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H/E:U/RL:O/RC:C

Exploitation evidence

  1. Disclosed: evidence found.

    CVE published 9 Jun 2026

  2. Detectable: no evidence on record.

    No public nuclei template indexed

  3. Weaponized: no evidence on record.

    No public exploit code indexed in Metasploit or Exploit-DB

  4. Exploited in the wild: no evidence on record.

    Not in CISA KEV and no source reports exploitation

  5. Observed by OffSeq Mirage: no evidence on record.

    No attack traffic recorded by OffSeq Mirage sensors

A missing step is not evidence of safety. Sources: cve.org (opens in a new tab), the Metasploit, Exploit-DB and nuclei-templates index as of 29 Oct 2026.

What to do

Upgrade Microsoft Office to 16.0.5556.1001 (2016) or 16.110.26061317 (365 for Mac, LTSC for Mac 2021, LTSC for Mac 2024).

Affected software

ProductAffectedFixed in
MicrosoftMicrosoft 365 Apps for EnterpriseAffected
  • =16.0.1
Fixed in–
MicrosoftMicrosoft Office 2016Affected
  • >=16.0.0 <16.0.5556.1001
Fixed in
  • 16.0.5556.1001
MicrosoftMicrosoft Office 2019Affected
  • =19.0.0
Fixed in–
MicrosoftMicrosoft Office 365 for MacAffected
  • >=1.0.0 <16.110.26061317
Fixed in
  • 16.110.26061317
MicrosoftMicrosoft Office LTSC 2021Affected
  • =16.0.1
Fixed in–
MicrosoftMicrosoft Office LTSC 2024Affected
  • =16.0.0
Fixed in–

AI-suggested

An official fix is available from Microsoft. Since this is a cloud-hosted service, Microsoft manages the remediation server-side. Users and administrators should apply the official updates as directed in the Microsoft advisory at https://msrc.microsoft.com/update-guide/vulnerability/CVE-2026-45645 to ensure protection.

Description

Untrusted pointer dereference in Microsoft Office allows an unauthorized attacker to execute code locally.

References

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