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CVE-2026-100843VulnerabilityPublished

MONAI versions before 1.6.0 contain a remote code execution vulnerability in the algo_from_pickle() function due to

Source GCVE Database

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Authoritative record:CVE-2026-100843· High 8.5

Not known to be exploited · CVSS 8.5 High : upgrade to 1.6.0 soon.

Data as of 9 Nov 2026, 23:24 UTC

CVSS 4.0 base score
8.5High
How severe the flaw is on the 0–10 CVSS scale.
EPSS
0.3% chance of exploitation in 30 days – higher than 23% of CVEsExploit Prediction Scoring System: the likelihood attackers will use this flaw soon.
Patch
Available – fixed in 1.6.0
CVSS:4.0/AV:L/AC:L/AT:N/PR:N/UI:P/VC:H/VI:H/VA:H/SC:N/SI:N/SA:N

Exploitation evidence

t = 0 is the CVE’s publication on cve.org

  1. Disclosed: evidence found.

    CVE published 27 Sep 2026

  2. Detectable: no evidence on record.

    No public nuclei template indexed

  3. Weaponized: evidence found.

    CISA SSVC: proof of concept public

  4. Exploited in the wild: no evidence on record.

    Not in CISA KEV and no source reports exploitation

  5. Observed by OffSeq Mirage: no evidence on record.

    No attack traffic recorded by OffSeq Mirage sensors

Timeline

  1. CVE ID reserved

    by VulnCheck

    , 1 hour before disclosure

  2. CVE published

    on cve.org

    , t = 0

  3. CISA SSVC assessment

    proof of concept public

    , 3 days after disclosure

  4. In Threat Radar

    record ingested

    , 29 days after disclosure

A missing step is not evidence of safety. Sources: cve.org (opens in a new tab), CISA SSVC, the Metasploit, Exploit-DB and nuclei-templates index as of 9 Nov 2026.

What to do

Upgrade MONAI to 1.6.0.

Affected software

ProductAffectedFixed in
Project-MONAIMONAIAffected
  • <1.6.0
Fixed in
  • 1.6.0
PyPIMONAIpkg:pypi/MONAIOther threatsAffected
  • <1.6.0
Fixed in
  • 1.6.0

Check your own hosts for these packages with threat-finder (opens in a new tab), our free open-source scanner.

AI-suggested

If you cannot patch yet, avoid deserializing untrusted pickle files with the vulnerable function to prevent exploitation.

Description

MONAI versions before 1.6.0 have a remote code execution vulnerability in the algo_from_pickle() function due to unsafe deserialization of pickle files. This flaw allows attackers to craft malicious pickle files that, when deserialized, execute arbitrary system commands. The vulnerability is identified as CWE-502 and has a high severity CVSS score of 7.8.

References

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