CVE-2025-10355VulnerabilityPublished 23 Oct 2025

CVE-2025-10355: MOLGENIS EMX2 · Open Redirect

Affects MOLGENIS EMX2Source CVE Database V5

Not known to be exploited · CVSS 5.1 Medium.

Data as of 26 Oct 2026, 06:26 UTC

CVSS 4.0 base score

5.1Medium

How severe the flaw is on the 0–10 CVSS scale.

EPSS: 0.3% chance of exploitation in 30 days – higher than 23% of CVEsExploit Prediction Scoring System: the likelihood attackers will use this flaw soon.

CVSS:4.0/AV:N/AC:L/AT:N/PR:N/UI:A/VC:N/VI:N/VA:N/SC:L/SI:L/SA:N

Attack Vector: Network
Attack Complexity: Low
Attack Requirements: None
Privileges Required: None
User Interaction: Active
Vulnerable system confidentiality: None
Vulnerable system integrity: None
Vulnerable system availability: None
Subsequent system confidentiality: Low
Subsequent system integrity: Low
Subsequent system availability: None

Bold values are the worst case: easiest to exploit or largest impact.

Attack Vector: Network: The vulnerable system is bound to the network stack and the set of possible attackers extends beyond the other options listed below, up to and including the entire Internet. Such a vulnerability is often termed “remotely exploitable” and can be thought of as an attack being exploitable at the protocol level one or more network hops away (e.g., across one or more routers).
Attack Complexity: Low: The attacker must take no measurable action to exploit the vulnerability. The attack requires no target-specific circumvention to exploit the vulnerability. An attacker can expect repeatable success against the vulnerable system.
Attack Requirements: None: The successful attack does not depend on the deployment and execution conditions of the vulnerable system. The attacker can expect to be able to reach the vulnerability and execute the exploit under all or most instances of the vulnerability.
Privileges Required: None: The attacker is unauthorized prior to attack, and therefore does not require any access to settings or files of the vulnerable system to carry out an attack.
User Interaction: Active: Successful exploitation of this vulnerability requires a targeted user to perform specific, conscious interactions with the vulnerable system and the attacker’s payload, or the user’s interactions would actively subvert protection mechanisms which would lead to exploitation of the vulnerability.
Vulnerable system confidentiality: None: There is no loss of confidentiality within the Vulnerable System.
Vulnerable system integrity: None: There is no loss of integrity within the Vulnerable System.
Vulnerable system availability: None: There is no impact to availability within the Vulnerable System.
Subsequent system confidentiality: Low: There is some loss of confidentiality. Access to some restricted information is obtained, but the attacker does not have control over what information is obtained, or the amount or kind of loss is limited. The information disclosure does not cause a direct, serious loss to the Subsequent System.
Subsequent system integrity: Low: Modification of data is possible, but the attacker does not have control over the consequence of a modification, or the amount of modification is limited. The data modification does not have a direct, serious impact to the Subsequent System.
Subsequent system availability: None: There is no impact to availability within the Subsequent System or all availability impact is constrained to the Vulnerable System.

Definitions: FIRST CVSS v4.0 specification.

Exploitation evidence

Disclosed: evidence found.
CVE published 23 Oct 2025
Detectable: no evidence on record.
No public nuclei template indexed
Weaponised: no evidence on record.
No public exploit code indexed in Metasploit or Exploit-DB
Exploited in the wildExploited: no evidence on record.
Not in CISA KEV and no source reports exploitation
Observed by OffSeq MirageSeen by Mirage: no evidence on record.
No attack traffic recorded by OffSeq Mirage sensors

A missing step is not evidence of safety. Sources: cve.org (opens in a new tab), the Metasploit, Exploit-DB and nuclei-templates index as of 2026-10-26.

Disclosed: The CVE record is public on cve.org. Its publication is t = 0.
Detectable: A public nuclei template can find exposed instances, for defenders and attackers alike.
Weaponised: Public exploit code exists in Metasploit or Exploit-DB, or CISA SSVC reports a public proof of concept.
Exploited in the wild: CISA KEV lists it, CISA SSVC rates exploitation active, or a source reports attacks.
Observed by OffSeq Mirage: OffSeq Mirage honeypot sensors recorded attack traffic for this CVE, or found exposed hosts without attack traffic.

Moments are spaced evenly, not to scale; a dashed line marks a gap of six months or more. Deltas count from t = 0. Sources that give only a date (CISA KEV, Exploit-DB, or a time of exactly 00:00Z) read “same day” rather than hours. Metasploit modules carry the flaw’s disclosure date, not their release date, and nuclei templates carry no date, so both appear above but not on the timeline.

What to do

Affected software

Product	Affected	Fixed in
MOLGENIS MOLGENIS EMX2	Affected =11.14.0	Fixed in–

AI-suggested

Organizations should implement strict validation and sanitization of all URL redirection parameters within MOLGENIS EMX2 to ensure only trusted internal URLs are allowed. Employ allowlists for redirect destinations rather than blacklists to prevent bypass via encoding tricks like %2f%2f. Until an official patch is released, consider deploying web application firewalls (WAFs) with rules to detect and block suspicious redirect patterns. Conduct user awareness training focused on recognizing phishing attempts and suspicious URLs, emphasizing caution when clicking links from untrusted sources. Monitor logs for unusual redirect requests and investigate any anomalies promptly. If feasible, restrict external URL redirection functionality or disable it temporarily. Engage with MOLGENIS vendor support to obtain updates or patches and apply them promptly once available. Additionally, implement multi-factor authentication (MFA) on user accounts to mitigate the impact of credential theft resulting from phishing.

Description

Open redirection vulnerability in MOLGENIS EMX2 v11.14.0. This vulnerability allows an attacker to create a malicious URL using a manipulated redirection parameter, potentially leading users to phishing sites or other malicious destinations via “/%2f%2f<MALICIOUS_DOMAIN>”.

Impact

For European organizations, especially those in biomedical research, healthcare, and data management sectors using MOLGENIS EMX2, this vulnerability poses a risk of phishing and social engineering attacks. Successful exploitation could lead to credential theft, unauthorized access to sensitive research data, and potential malware infections. The indirect impact includes reputational damage, loss of trust among collaborators, and possible regulatory consequences under GDPR if personal or sensitive data is compromised. Since MOLGENIS is used in research institutions across Europe, the vulnerability could disrupt collaborative projects and data sharing. Although the vulnerability does not directly compromise system integrity or availability, the redirection can facilitate attacks that do. The lack of authentication requirement and ease of exploitation increase the risk, especially if users are not trained to recognize suspicious URLs. The absence of known exploits in the wild reduces immediate risk but does not eliminate the threat, as attackers could develop exploits rapidly once the vulnerability is public.

CWE-601URL Redirection to Untrusted Site ('Open Redirect') (opens in a new tab)
Base weaknessLikelihood of exploit: LowOWASP Top 10 A01:2025: Broken Access Control (opens in a new tab)
The web application accepts a user-controlled input that specifies a link to an external site, and uses that link in a redirect.
Implementation · Input Validation
Assume all input is malicious. Use an "accept known good" input validation strategy, i.e., use a list of acceptable inputs that strictly conform to specifications. Reject any input that does not strictly conform to specifications, or transform it into something that does.
Architecture and Design
Use an intermediate disclaimer page that provides the user with a clear warning that they are leaving the current site. Implement a long timeout before the redirect occurs, or force the user to click on the link. Be careful to avoid XSS problems (CWE-79) when generating the disclaimer page.
Architecture and Design · Enforcement by Conversion
When the set of acceptable objects, such as filenames or URLs, is limited or known, create a mapping from a set of fixed input values (such as numeric IDs) to the actual filenames or URLs, and reject all other inputs.
OWASP Cheat Sheets
Mass Assignment (opens in a new tab)
Authorization (opens in a new tab)
OWASP ASVS 4.0.3
V5.1.5 (opens in a new tab)
Attack patterns
Cross-Site Flashing (opens in a new tab)
From MITRE CWE, MITRE CAPEC and OWASP (Top 10, OpenCRE).

References

incibe.es/en/incibe-cert/notices/aviso/open-redirection-vulnerability-molgenis-emx2 (opens in a new tab)

Community reviews

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Exploitation evidence

What to do

Affected software

Description

AI analysisMachine-generated, updated 23 Oct 2025, 12:00 UTC

WeaknessesCWE-601

Technical details

References

Community reviews

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