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VulnerabilityPublished Updated

CVE-2026-54604: libtiff · Prior to 4.0.1, a behavior change

Affects openslideSource GCVE Database

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Not known to be exploited · CVSS 5.3 Medium · fixed in 4.0.1 : update openslide when convenient.

Data as of 8 Nov 2026, 23:24 UTC

CVSS 4.0 base score
5.3Medium
How severe the flaw is on the 0–10 CVSS scale.
EPSS
0.5% chance of exploitation in 30 days – higher than 44% of CVEsExploit Prediction Scoring System: the likelihood attackers will use this flaw soon.
Patch
Available – fixed in 4.0.1
CVSS:4.0/AV:N/AC:L/AT:N/PR:L/UI:N/VC:L/VI:N/VA:N/SC:N/SI:N/SA:N

Exploitation evidence

  1. Disclosed: evidence found.

    CVE published 17 Sep 2026

  2. Detectable: no evidence on record.

    No public nuclei template indexed

  3. Weaponized: no evidence on record.

    No public exploit code indexed in Metasploit or Exploit-DB

  4. Exploited in the wild: no evidence on record.

    Not in CISA KEV and no source reports exploitation

  5. Observed by OffSeq Mirage: no evidence on record.

    No attack traffic recorded by OffSeq Mirage sensors

A missing step is not evidence of safety. Sources: cve.org (opens in a new tab), the Metasploit, Exploit-DB and nuclei-templates index as of 9 Nov 2026.

What to do

Affected software

ProductAffectedFixed in
Ubuntu 26.10openslidepkg:deb/ubuntu/openslide?arch=source&distro=stonkingOther threatsAffected
  • =3.4.1+dfsg-7build4
  • =3.4.1+dfsg-9
Fixed in–
Ubuntu 26.04 LTSopenslidepkg:deb/ubuntu/openslide?arch=source&distro=resoluteOther threatsAffected
  • =3.4.1+dfsg-7build3
  • =3.4.1+dfsg-7build4
Fixed in–
Ubuntu 25.10openslidepkg:deb/ubuntu/openslide?arch=source&distro=questingOther threatsAffected
  • =3.4.1+dfsg-7build2
  • =3.4.1+dfsg-7build3
Fixed in–
Ubuntu 24.04 LTSopenslidepkg:deb/ubuntu/openslide?arch=source&distro=nobleOther threatsAffected
  • 3.4.1+dfsg-6build1 – 3.4.1+dfsg-7build2
4 affected builds
Fixed in–
Ubuntu 22.04 LTSopenslidepkg:deb/ubuntu/openslide?arch=source&distro=jammyOther threatsAffected
  • =3.4.1+dfsg-5
  • =3.4.1+dfsg-5build1
Fixed in–
Ubuntu 20.04 LTSopenslidepkg:deb/ubuntu/openslide?arch=source&distro=focalOther threatsAffected
  • =3.4.1+dfsg-4
Fixed in–

Check your own hosts for these packages with threat-finder (opens in a new tab), our free open-source scanner.

AI-suggested

Upgrade OpenSlide to version 4.0.1 or the official binary build 4.0.0.12 to remediate this vulnerability. No other mitigation is indicated by the vendor advisory.

Description

OpenSlide versions prior to 4.0.1 have a vulnerability due to a behavior change in libtiff 4.7.1 affecting TIFF tile path handling. This flaw can cause uninitialized heap memory to be included in pixel data returned by openslide_read_region() when processing crafted TIFF-based slides (excluding Hamamatsu NDPI). The issue is resolved in OpenSlide 4.0.1 and official binary build 4.0.0.12.

References

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