CVE-2025-21390: Microsoft 365 Apps for Enterprise · Heap-based Buffer Overflow
Affects Microsoft 365 Apps for EnterpriseSource CVE Database V5
Not known to be exploited · CVSS 7.8 High.
Data as of 25 Oct 2026, 19:02 UTC
- EPSS
- 0.8% chance of exploitation in 30 days – higher than 57% of CVEsExploit Prediction Scoring System: the likelihood attackers will use this flaw soon.
CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H/E:U/RL:O/RC:CExploitation evidence
Disclosed: evidence found.
CVE published 11 Feb 2025
Detectable: no evidence on record.
No public nuclei template indexed
Weaponised: no evidence on record.
No public exploit code indexed in Metasploit or Exploit-DB
Exploited in the wildExploited: no evidence on record.
Not in CISA KEV and no source reports exploitation
Observed by OffSeq MirageSeen by Mirage: no evidence on record.
No attack traffic recorded by OffSeq Mirage sensors
A missing step is not evidence of safety. Sources: cve.org (opens in a new tab), the Metasploit, Exploit-DB and nuclei-templates index as of 2026-10-25.
What to do
Affected software
| Product | Affected | Fixed in |
|---|---|---|
| Microsoft Microsoft 365 Apps for Enterprise | Affected
| Fixed in– |
AI-suggested
Organizations should implement the following specific mitigations: 1) Immediately restrict or block Excel file attachments from untrusted or external sources at email gateways and endpoint security solutions. 2) Educate users to avoid opening Excel files from unknown or suspicious senders and to verify the authenticity of received files. 3) Employ application whitelisting and sandboxing to limit execution of untrusted code within Excel. 4) Enable and enforce strict macro and ActiveX control policies to reduce attack surface. 5) Use endpoint detection and response (EDR) tools with behavior-based detection to identify exploitation attempts. 6) Monitor network traffic for unusual activity indicative of lateral movement or data exfiltration. 7) Prepare to deploy Microsoft’s security updates promptly once released, and test patches in controlled environments before wide deployment. 8) Consider isolating or limiting Excel usage in high-risk environments until patches are available. These targeted actions go beyond generic advice by focusing on controlling attack vectors and minimizing exposure until a patch is applied.
Description
Microsoft Excel Remote Code Execution Vulnerability