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CVE-2026-22186VulnerabilityPublished Updated

CVE-2026-22186: Open Microscopy Environment Bio-Formats · XML External Entity (XXE)

Affects Open Microscopy Environment Bio-FormatsSource CVE Database V5

0

Not known to be exploited · CVSS 4.6 Medium.

Data as of 26 Oct 2026, 06:26 UTC

CVSS 4.0 base score
4.6Medium
How severe the flaw is on the 0–10 CVSS scale.
EPSS
0.1% chance of exploitation in 30 days – higher than 6% of CVEsExploit Prediction Scoring System: the likelihood attackers will use this flaw soon.
CVSS:4.0/AV:L/AC:L/AT:N/PR:N/UI:A/VC:L/VI:N/VA:L/SC:N/SI:N/SA:N

Exploitation evidence

  1. Disclosed: evidence found.

    CVE published 7 Jan 2026

  2. Detectable: no evidence on record.

    No public nuclei template indexed

  3. Weaponised: no evidence on record.

    No public exploit code indexed in Metasploit or Exploit-DB

  4. Exploited in the wild: no evidence on record.

    Not in CISA KEV and no source reports exploitation

  5. Observed by OffSeq Mirage: no evidence on record.

    No attack traffic recorded by OffSeq Mirage sensors

A missing step is not evidence of safety. Sources: cve.org (opens in a new tab), the Metasploit, Exploit-DB and nuclei-templates index as of 2026-10-26.

What to do

Affected software

ProductAffectedFixed in
Open Microscopy EnvironmentBio-FormatsAffected
  • <=8.3.0
Fixed in–
GitHubome/bioformatspkg:github/ome/bioformatsOther threatsAffected
  • =0
  • <=8.3.0
Fixed in–

Check your own hosts for these packages with threat-finder (opens in a new tab), our free open-source scanner.

AI-suggested

Until an official fix is available, avoid processing untrusted Leica XML metadata files with vulnerable Bio-Formats versions. Monitor vendor communications for updates on patches or mitigations.

Description

Bio-Formats versions up to and including 8.3.0 contain an XML External Entity (XXE) vulnerability in the Leica Microsystems metadata parsing component (e.g., XLEF). The parser uses an insecurely configured DocumentBuilderFactory when processing Leica XML-based metadata files, allowing external entity expansion and external DTD loading. A crafted metadata file can trigger outbound network requests (SSRF), access local system resources where readable, or cause a denial of service during XML parsing.

References

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