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VulnerabilityPublished Updated

CVE-2025-21397: Microsoft 365 Apps for Enterprise · Use After Free

Affects Microsoft 365 Apps for EnterpriseSource CVE Database V5

0

Not known to be exploited · CVSS 7.8 High.

Data as of 26 Oct 2026, 17:16 UTC

CVSS 3.1 base score
7.8High
How severe the flaw is on the 0–10 CVSS scale.
EPSS
0.7% chance of exploitation in 30 days – higher than 55% of CVEsExploit Prediction Scoring System: the likelihood attackers will use this flaw soon.
CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H/E:U/RL:O/RC:C

Exploitation evidence

  1. Disclosed: evidence found.

    CVE published 11 Feb 2025

  2. Detectable: no evidence on record.

    No public nuclei template indexed

  3. Weaponised: no evidence on record.

    No public exploit code indexed in Metasploit or Exploit-DB

  4. Exploited in the wild: no evidence on record.

    Not in CISA KEV and no source reports exploitation

  5. Observed by OffSeq Mirage: no evidence on record.

    No attack traffic recorded by OffSeq Mirage sensors

A missing step is not evidence of safety. Sources: cve.org (opens in a new tab), the Metasploit, Exploit-DB and nuclei-templates index as of 26 Oct 2026.

What to do

Affected software

ProductAffectedFixed in
Microsoft Microsoft 365 Apps for EnterpriseAffected
  • =16.0.1
Fixed in–

AI-suggested

Until an official patch is released, organizations should implement specific mitigations: 1) Educate users to avoid opening unsolicited or suspicious files, especially from untrusted sources. 2) Employ advanced email filtering and attachment sandboxing to detect and block malicious files. 3) Restrict the use of Microsoft 365 Apps for Enterprise version 16.0.1 on sensitive or high-risk systems where possible. 4) Use application control policies (e.g., Microsoft Defender Application Control) to limit execution of untrusted code. 5) Monitor endpoint behavior for signs of exploitation attempts, including unusual memory usage or crashes. 6) Maintain up-to-date backups and incident response plans to mitigate potential damage. 7) Prepare for rapid deployment of patches once Microsoft releases updates addressing this vulnerability.

Description

Microsoft Office Remote Code Execution Vulnerability

References

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