CVE-2025-21397: Microsoft 365 Apps for Enterprise · Use After Free
Affects Microsoft 365 Apps for EnterpriseSource CVE Database V5
Not known to be exploited · CVSS 7.8 High.
Data as of 26 Oct 2026, 10:12 UTC
- EPSS
- 0.7% chance of exploitation in 30 days – higher than 55% of CVEsExploit Prediction Scoring System: the likelihood attackers will use this flaw soon.
CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H/E:U/RL:O/RC:CExploitation evidence
Disclosed: evidence found.
CVE published 11 Feb 2025
Detectable: no evidence on record.
No public nuclei template indexed
Weaponised: no evidence on record.
No public exploit code indexed in Metasploit or Exploit-DB
Exploited in the wildExploited: no evidence on record.
Not in CISA KEV and no source reports exploitation
Observed by OffSeq MirageSeen by Mirage: no evidence on record.
No attack traffic recorded by OffSeq Mirage sensors
A missing step is not evidence of safety. Sources: cve.org (opens in a new tab), the Metasploit, Exploit-DB and nuclei-templates index as of 26 Oct 2026.
What to do
Affected software
| Product | Affected | Fixed in |
|---|---|---|
| Microsoft Microsoft 365 Apps for Enterprise | Affected
| Fixed in– |
AI-suggested
Until an official patch is released, organizations should implement specific mitigations: 1) Educate users to avoid opening unsolicited or suspicious files, especially from untrusted sources. 2) Employ advanced email filtering and attachment sandboxing to detect and block malicious files. 3) Restrict the use of Microsoft 365 Apps for Enterprise version 16.0.1 on sensitive or high-risk systems where possible. 4) Use application control policies (e.g., Microsoft Defender Application Control) to limit execution of untrusted code. 5) Monitor endpoint behavior for signs of exploitation attempts, including unusual memory usage or crashes. 6) Maintain up-to-date backups and incident response plans to mitigate potential damage. 7) Prepare for rapid deployment of patches once Microsoft releases updates addressing this vulnerability.
Description
Microsoft Office Remote Code Execution Vulnerability