CVE-2025-63527 identifies a cross-site scripting (XSS) vulnerability in the Blood Bank Management System version 1.0, specifically within the updateprofile.php and hprofile.php components. The root cause is the failure to properly sanitize or encode user-supplied inputs before rendering them in HTTP responses. The vulnerable parameters include hname, hemail, hpassword, hphone, and hcity, which accept user input that is reflected back without adequate filtering. This flaw allows an attacker with low privileges to inject malicious JavaScript payloads that execute in the victim's browser when they view the affected pages. The vulnerability has a CVSS 3.1 score of 8.5, indicating high severity, with an attack vector of network (remote exploitation), low attack complexity, no user interaction required, and partial impact on confidentiality and integrity. The scope is changed, meaning the vulnerability can affect resources beyond the initially vulnerable component. Although no exploits have been observed in the wild, the vulnerability poses a significant risk to confidentiality, as attackers can steal session cookies, perform actions on behalf of users, or conduct phishing attacks. The lack of authentication requirement for exploitation further increases the threat. This vulnerability is particularly concerning in healthcare environments where sensitive patient data is managed, and the Blood Bank Management System is used to handle critical blood donation and transfusion records. The absence of patches at the time of disclosure necessitates immediate mitigation efforts by organizations using this software.

For European organizations, especially those in the healthcare sector using the Blood Bank Management System, this vulnerability could lead to severe confidentiality breaches, including unauthorized access to sensitive patient and donor information. Attackers could hijack user sessions, manipulate user profiles, or inject malicious scripts that compromise the integrity of the system or facilitate further attacks such as phishing or malware distribution. The disruption of blood bank operations could have direct consequences on patient care and safety. Given the high sensitivity of healthcare data under GDPR, exploitation could also result in significant regulatory penalties and reputational damage. The vulnerability's ease of exploitation and lack of need for user interaction increase the risk of widespread attacks if the system is exposed to the internet or accessible within internal networks. European healthcare providers must consider the operational and compliance impacts, as well as the potential for cascading effects on related healthcare services.

Organizations should immediately implement strict input validation and output encoding on all user-supplied data, particularly for the affected parameters (hname, hemail, hpassword, hphone, hcity) in updateprofile.php and hprofile.php. Employing Content Security Policy (CSP) headers can help mitigate the impact of injected scripts. Network segmentation and access controls should limit exposure of the Blood Bank Management System to trusted users only. Monitoring and logging of web application activity should be enhanced to detect anomalous requests indicative of exploitation attempts. Since no official patches are currently available, organizations should engage with the software vendor for updates and consider temporary workarounds such as web application firewalls (WAFs) configured to block suspicious input patterns. User education on phishing risks and session management best practices can reduce the impact of successful exploitation. Finally, conducting regular security assessments and penetration tests on the system will help identify and remediate similar vulnerabilities proactively.