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VulnerabilityPublished Updated

CVE-2025-21346: Microsoft 365 Apps for Enterprise · Protection Mechanism Failure

Affects Microsoft 365 Apps for EnterpriseSource CVE Database V5

0

Not known to be exploited · CVSS 7.1 High · patch available : patch Microsoft 365 Apps for Enterprise soon.

Data as of 26 Oct 2026, 14:05 UTC

CVSS 3.1 base score
7.1High
How severe the flaw is on the 0–10 CVSS scale.
EPSS
0.7% chance of exploitation in 30 days – higher than 52% of CVEsExploit Prediction Scoring System: the likelihood attackers will use this flaw soon.
Patch
Available
CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:N/I:H/A:H/E:U/RL:O/RC:C

Exploitation evidence

  1. Disclosed: evidence found.

    CVE published 14 Jan 2025

  2. Detectable: no evidence on record.

    No public nuclei template indexed

  3. Weaponised: no evidence on record.

    No public exploit code indexed in Metasploit or Exploit-DB

  4. Exploited in the wild: no evidence on record.

    Not in CISA KEV and no source reports exploitation

  5. Observed by OffSeq Mirage: no evidence on record.

    No attack traffic recorded by OffSeq Mirage sensors

A missing step is not evidence of safety. Sources: cve.org (opens in a new tab), the Metasploit, Exploit-DB and nuclei-templates index as of 26 Oct 2026.

What to do

Affected software

ProductAffectedFixed in
Microsoft Microsoft 365 Apps for EnterpriseAffected
  • 16.0.1
Fixed in–

AI-suggested

Microsoft has released an official fix for this vulnerability. Since Microsoft 365 Apps for Enterprise is a cloud service, Microsoft manages the remediation server-side. Users and administrators should ensure their environments are updated according to the vendor advisory at https://msrc.microsoft.com/update-guide/vulnerability/CVE-2025-21346 to apply the fix.

Description

Microsoft Office Security Feature Bypass Vulnerability

References

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