CVE-2025-59221: Microsoft 365 Apps for Enterprise · Use After Free
Affects Microsoft 365 Apps for EnterpriseSource CVE Database V5
Not known to be exploited · CVSS 7.0 High.
Data as of 25 Oct 2026, 19:02 UTC
- EPSS
- 0.3% chance of exploitation in 30 days – higher than 32% of CVEsExploit Prediction Scoring System: the likelihood attackers will use this flaw soon.
CVSS:3.1/AV:L/AC:H/PR:N/UI:R/S:U/C:H/I:H/A:H/E:U/RL:O/RC:CExploitation evidence
Disclosed: evidence found.
CVE published 14 Oct 2025
Detectable: no evidence on record.
No public nuclei template indexed
Weaponised: no evidence on record.
No public exploit code indexed in Metasploit or Exploit-DB
Exploited in the wildExploited: no evidence on record.
Not in CISA KEV and no source reports exploitation
Observed by OffSeq MirageSeen by Mirage: no evidence on record.
No attack traffic recorded by OffSeq Mirage sensors
A missing step is not evidence of safety. Sources: cve.org (opens in a new tab), the Metasploit, Exploit-DB and nuclei-templates index as of 2026-10-25.
What to do
Affected software
| Product | Affected | Fixed in |
|---|---|---|
| Microsoft Microsoft 365 Apps for Enterprise | Affected
| Fixed in– |
AI-suggested
1. Apply official patches from Microsoft immediately once they become available for Microsoft 365 Apps for Enterprise version 16.0.1. 2. Until patches are released, restrict local access to systems running the affected software to trusted users only. 3. Implement application whitelisting and control to prevent execution of unauthorized code or scripts. 4. Educate users to avoid opening suspicious or unsolicited documents, especially from unknown sources. 5. Use endpoint detection and response (EDR) tools to monitor for unusual behavior indicative of exploitation attempts. 6. Employ network segmentation to limit lateral movement if a system is compromised. 7. Regularly update and audit software inventories to ensure vulnerable versions are identified and remediated promptly. 8. Consider disabling or restricting macros and embedded content in Office documents where possible to reduce attack surface.
Description
Use after free in Microsoft Office Word allows an unauthorized attacker to execute code locally.