CVE-2025-21386: Microsoft 365 Apps for Enterprise · Use After Free
Affects Microsoft 365 Apps for EnterpriseSource CVE Database V5
Not known to be exploited · CVSS 7.8 High.
Data as of 26 Oct 2026, 06:26 UTC
- EPSS
- 0.8% chance of exploitation in 30 days – higher than 57% of CVEsExploit Prediction Scoring System: the likelihood attackers will use this flaw soon.
CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H/E:U/RL:O/RC:CExploitation evidence
Disclosed: evidence found.
CVE published 11 Feb 2025
Detectable: no evidence on record.
No public nuclei template indexed
Weaponised: no evidence on record.
No public exploit code indexed in Metasploit or Exploit-DB
Exploited in the wildExploited: no evidence on record.
Not in CISA KEV and no source reports exploitation
Observed by OffSeq MirageSeen by Mirage: no evidence on record.
No attack traffic recorded by OffSeq Mirage sensors
A missing step is not evidence of safety. Sources: cve.org (opens in a new tab), the Metasploit, Exploit-DB and nuclei-templates index as of 2026-10-26.
What to do
Affected software
| Product | Affected | Fixed in |
|---|---|---|
| Microsoft Microsoft 365 Apps for Enterprise | Affected
| Fixed in– |
AI-suggested
Until an official patch is released, organizations should implement several specific mitigations: 1) Enforce strict email and file attachment filtering to block or quarantine Excel files from untrusted or unknown sources. 2) Educate users about the risks of opening unsolicited or suspicious Excel documents, emphasizing the importance of verifying file origins. 3) Deploy application control or whitelisting solutions to restrict execution of untrusted macros or code within Excel. 4) Utilize Microsoft Defender for Office 365 and endpoint detection and response (EDR) tools to detect and block exploitation attempts. 5) Apply the principle of least privilege to limit user permissions, reducing the impact of potential code execution. 6) Monitor network and endpoint logs for unusual behavior indicative of exploitation attempts. 7) Prepare for rapid deployment of the official patch once available by maintaining up-to-date asset inventories and testing environments. These targeted actions go beyond generic advice by focusing on the specific attack vector and exploitation method of this vulnerability.
Description
Microsoft Excel Remote Code Execution Vulnerability